Rac Activation by the T-Cell Receptor Inhibits T Cell Migration
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چکیده
منابع مشابه
Rac Activation by the T-Cell Receptor Inhibits T Cell Migration
BACKGROUND T cell migration is essential for immune responses and inflammation. Activation of the T-cell receptor (TCR) triggers a migration stop signal to facilitate interaction with antigen-presenting cells and cell retention at inflammatory sites, but the mechanisms responsible for this effect are not known. METHODOLOGY/PRINCIPAL FINDINGS Migrating T cells are polarized with a lamellipodiu...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0012393